منابع مشابه
Toxicology: judge data or dollars?
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Given the central importance of ubiquitin to proteoly-sis, it is somewhat ironic that the first protein shown to The University of Chicago Department of Biochemistry and Molecular Biology be modified by ubiquitin was histone H2A, a polypeptide that is degraded only very slowly in vivo (Goldknopf and 920 East 58th Street Chicago, Illinois 60637 Busch, 1977). In this and more recent examples (see...
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The liver is the largest internal organ in the human body that is responsible for more than 500 vital functions, including biosynthesis of major plasma proteins, immunity against infectious pathogens, balancing energy metabolism and xenobiotics biotransformation (1). One of the main functions of the liver is an important role in drug metabolism (2). Since developing new drug compounds into mark...
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A brief history of the development of the field of aquatic toxicology is provided. In order to provide a perspective on the state-of-the-art in aquatic toxicology relative to classical toxicology, the two fields are compared from the standpoint of the type of scientist practicing each field, the respective objectives of each, the forces which drive the activity in each field, and the major adva...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1999
ISSN: 0091-6765
DOI: 10.2307/3454555